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    Contents lists available at ScienceDirect
    Clinical Radiology
    An analysis of 11.3 million screening tests examining the association between needle biopsy rates and cancer detection rates in the English NHS Breast Cancer Screening Programme
    a Cancer Epidemiology Unit, Nuffield Department of Population Health, Oxford University, Richard Doll Building, Roosevelt Drive, Oxford, OX3 7LF, UK b Department of Radiology, St Georges University Hospital Foundation Trust, UK
    c Breast Screening Programme, Public Health England, London, UK
    d Cambridge Breast Unit, NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Trust, UK
    article in formation
    AIM: To examine the association between recall, needle biopsy, and cancer detection rates to inform the setting of target ranges to optimise the benefit to harm ratio of breast screening programmes.
    MATERIALS AND METHODS: Annual screening programme information from 2009/10 to 2015/16 for the 80 screening units of the English National Health Service Breast Screening Programme (totalling 11.3 million screening tests) was obtained from annual (KC62) returns. Linear regression models were used to examine the association between needle biopsy rates and recall rates and non-linear regression models to examine the association between cancer detection rates and needle biopsy rates.